Approch Background

Background

The ability of eye to take in light and transduce it into signals, which can be transmitted and form images in the brain, is depended on photoreceptors – the light-sensing cells in the retina.  The photoreceptors are nurtured and supported by a thin cell layer known as retinal pigment epithelium (RPE).  When the retina becomes damaged as a result of injury or disease, it cannot repair itself.  

Age-related macular degeneration (AMD) is an acquired retinal degenerative disease.  It is characterized by the loss of RPE initially and the subsequently loss of photoreceptors.  Stargardt’s Disease (SD) and Retinitis Pigmentosa (RP) are inherited retinal degenerative diseases and usually diagnosed in children and young adults.  Both disorders cause the progressive damages of photoreceptors in retina.  By 2020, near 200 million people will develop AMD globally.  The less common hereditary forms of retinal disorders will strike several million others in their early stages of life. 

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